DNA sequences - IMGT/JunctionAnalysis
IMGT/JunctionAnalysis is an integrated analysis tool for the Immunoglobulin (IG) and T cell receptor (TR) JUNCTIONs.
IMGT/JunctionAnalysis analyses in a single search an unlimited number of junctions provided that the IMGT V-GENE and J-GENE and ALLELE names are identified.
The tool:
analyses junction nucleotide sequences of rearranged immunoglobulin (IGH, IGK or IGL) and T cell receptor (TRA, TRB, TRG or TRD) genes,
allows to set up parameters for accepted mutations in the IG 3’V-REGION, 5’J-REGION, and D-REGION
identifies accurately D-GENE and ALLELE in the IGH, TRB and TRD junctions,
delimits precisely the different regions of the junctions: V-REGION, D-REGION(s), J-REGION, as well as N-REGION(s) and P-REGION(s).
determines the number of mutations in the 3’ V-REGION, D-REGION and 5’ J-REGION of the IG JUNCTIONs.
calculates the "gc" content of the N-REGIONs of the IG and TR JUNCTIONs.